2012年5月21日星期一

The role of Hormone in Sex determination and differentiation

Sex hormone is another thorny issue in my theory system. Here firstly I want to claim that intersexuality, transgender, homosexuality and shemale are totally different conception in nature.

Intersexuality is identified as ambiguous genitals, commonly has a large clitoris or small penis. The reason is that crossing-over partial occurrence between X and Y chromosomes during father’s meiosis period then lead his offspring to be an intersex. Intersex is controlled by natural gene from parents, not by any sex hormones.

Transgender is identified who doesn’t identity his/her born gender, and do the surgery to artificially change the appearance, but not the genes. It obviously includes the psychological aspects, not only in the physiology. Not considering surgery (modern medicine), transgender is only identified as non-self-identity in psychology, and his/her body is as normal as male/female. I think psychological problem is also controlled by the natural gene.

Homosexuality is identified as who only loves the same gender as him/her self. It can be divided into two situations:
1, self-identity, it means he/she identifies him/her self as the born gender.
2, non-self-identity, it means he/she doesn’t identifies him/her self as the born gender, he/she wants to be the other gender.

Shemale is different from the three above. Famous shemales are always from Thailand, and most of them were from poor families and injected external estrogen when childhood. Ten years later, the male physical characteristics will gradually shrink, such as the male penis will become short and small, and the skin becomes nourish, the breast uplift. They look like as same as a normal female, but the genes they have is also XY.

Today I want to talk about the role of sex hormone which really suffered injustice. Human have two sex characteristics, one is called primary sexual characteristic, and the other is secondary sex characteristic.
1, Shape and structure of male and female genitals is called the primary sexual characteristic, decided by genetic material - chromosomes. It has been basically complete at the birth.
2, only the secondary sex characteristic is the result of sex hormones’ function in human.

There are almost no morphological differences between boys and girls before their puberty, although boys and girls still have testis and ovary. When entering puberty, the difference between men and women begin to appear with the increase of sex hormone levels. Estrogens are produced primarily by developing follicles in the ovaries, the corpus luteum, and the placenta. Follicle-stimulating hormone (FSH) stimulates the production of estrogen in the granulosa cells of the ovaries. Male levels of testosterone directly induce growth of the testicles and penis and indirectly (via dihydrotestosterone (DHT) the prostate. Estradiol and other hormones cause breasts to develop in females.

We can use logic way to reconsider that we can control the gender, if we think hormone is the key to intersex. If you want a boy, you can inject androgen from the beginning of your pregnant, and if you want a girl, you can inject estrogen. Do you think so? Absolutely not, it is so absurd. Hormone can do nothing in primary sexual characteristic. Primary sexual characteristic abnormal is only caused by genes. This is a causal question: Who decides who? Genes decide intersex or normal organs, then organs decide sex hormones secretion normal or abnormal.

I can give you another classic example here. There are some eunuchs in Chinese ancient palace whose penis and testis have been removed since he was little boy. I think the sex hormone in eunuch’s body have been in balance, neither androgen nor estrogen can prevail over each other. Notice here, these eunuchs are different from shemales, eunuchs don’t have testis, it means they can’t produce androgen, but they are not injected the external estrogen, so they neither show the male secondary sex characteristic, nor the female secondary sex characteristic. They look like enlarged version of little boy. The shemale is in different way. They still have penis and testis on his body, but they are injected estrogen since little boy, when entering puberty, they don’t show male secondary sex characteristic, but female secondary sex characteristic. Why do this happen? I think injection estrogen has destroyed the male normal sexual path, and secondary sex characteristic can’t be shown out under so much external estrogen, but they show some female secondary sex characteristic, such as breast uplift, slim waist and wide hips so forth and so on. They still have penis, testis, and scrotum, and penis can’t become into clitoris shaft, and scrotum still in fusion together can’t get into separated two piece labia majora, and the middle line is still in scrotum.

People always identify shemale as female, yes, they do look as same as female, but they are not real female and still have XY chromosomes. I made two pictures to illustrate the relationship between hormone and genes.

The above picture is the curve of human with XY chromosomes under different sex hormone. We can consider the black solid line as male physical normal development, and the red dotted line as shemale development. Androgen and estrogen almost get balance in blue dotted box, it also means the children whatever boys or girls before adolescence are under neutral appearance in the blue box, and you can’t even distinguish them by their face. When the androgen dominates, the boys get into masculinization, when the estrogen dominates, the boys get into shemale. Here I use anti-masculinization instead of feminization as same idea as particle and anti-particle, because I think if we use prefix “fe-” in the front of a word, it means she must be a she with XX, not XY. Masculinization and anti-masculinization here mean that the natures of them are same, just with different manifestations, as same as particle and anti-particle in physics.


Contrarily, the above picture is the curve of human with XX chromosomes under different sex hormone as the same idea as previous picture. We can consider the black solid line as female physical normal development, and the red dotted line as hefemale development. When the estrogen dominates, the girls get into feminization, when the androgen dominates, the girls get into hefemale. Here I use anti-feminization instead of masculinization, because I think if we use prefix “male-” in the front of a word, it means he must be a he with XY, not XX. Feminization and anti-feminization here mean that the natures of them are same, just with different manifestations.

2012年5月12日星期六

Is there a really big sex gap between male and female?


Men are From Mars, Women are From Venus. Most of common relationship problems people think between two genders are that they come from distinct planets. The way males fall in love is with their eyes, and the way females fall in love is with their ears. Male maybe can't understand in his whole life why so many women are full of vanity and comparing with other women. Women also feel inconceivable why men are so addicted to sex and beautiful young women. I am very serious to say that it is because they live in different frequencies and share the different values. The reason why women suffer vanity is that they are with empty soul, not only lose their selves, but also live in other people's evaluation, discussions and praise. The reason why men are addicted to sex so much is that they only care about their own like or dislike and do not care about other people's evaluation or discussion.

Frankly speaking, men are rational, and women are irrational. Male logic is more conform to the principles of game theory than female. Here I am not going to talk about the details why female are irrational, in short, women always can’t get the central idea of things including sex. Here I want to talk about there is a really big sex gap between male and female from the different genital pictures, when the God created human beings.

1, What can we get from external genitalia anatomy what we called deformity?
The above picture is a comparison of the normal and abnormal female genital. Apparently, so-called abnormal female genital looks like a little boy's genitals, with an enlarged clitoris, urethra and vagina fused into one tube, two labia fused together into scrotum with a raphe in the middle. Notice here, there is also a raphe there in normal man. It shows that two pieces of scrotum didn’t stick together at the beginning, but with the development of the fetus, two pieces get into fusion together. Female genital deformity, for some reasons so far unknown, just develop into the other side of gender in fertilized egg development process. It is easy to see that clitoris and penis are homologous, labia and scrotum are homologous.

The above picture is male genital feminization. We can obviously see that the penis with under developed didn’t grow out of the main body, and two pieces of scrotum didn’t get fusion successfully in fertilized egg development process for some reasons. This abnormal male genital looks very similar with normal female genital.

The above is the development of male and female external genitalia, it is clear that in the process of development, male and female genitals are both from the same organization and structure at the beginning. Only during the development, men and women have the different ways to develop. About why women and men suffer feminization and masculinization, many experts believe that the changes of virilization or feminization are due to androgen or estrogen. I have no idea, if so, I have a question: why the probability of abnormal genital is so low? Because the androgen or estrogen is a concept of quantitative, and every body has both, only in different proportion, how do you define the proportion? If hormone is the real reason to lead deformity, the incidence of deformity should not be so low.

I don’t know that, but I think there is another possibility, in the process of father's spermatogonia meiosis, some genital gene fragments of the XY chromosomes have allelic exchange partly, as the result is the gametes X or Y is not pure as normal and they get some gene fragments originally not belong to them. However, due to the male once ejaculate thousands of sperm, and the proportion of so-called abnormal sperm is very low compared with normal sperm, so it reduces very low probability of ambiguous genitalia. I think it would be a rational reason.



The left picture above is a normal female vulva anatomy, the right one is that I add something according to my situation (PS: I thought I am normal, but I just thought). I have a strong shaft up to the forefront of my pubis. Every time, I need to rub my shaft rhythmically to get my orgasm. What’s more important, I can feel a little ball obviously in my right labia majora, and the left one is smaller than the right one. The location of the ball is slightly higher than clitoris, but lower than the other side of my shaft. Not only a ball, I also can feel a stem up attached to the ball. It feels like the stem to an apple, I can say that the ball grow out of my body.
Do you think that is very interesting? Yes, I think so. Let me try another perspective.

2, What can we get from internal genitalia anatomy
,

As it is known to all, males can’t ejaculate and urinate at the same time. Current theory claimed that male body has a system that keeps it from being able to ejaculate and urinate at the same time. During sexual arousal, muscles at the base of the bladder contract in order to close off the passageway from the bladder into the urethra, the tube through which urine and semen leave the body. This makes it impossible for urine to be released during ejaculation. So, men can feel free to relax and go with the flow, because they don’t pee when they come. For women, things are more complicated, it is easy to confuse the sensation of impending orgasm with the urge to pee. This is more common that women suffer urinary stress incontinence when approaching orgasm. Simply, women are really confused by the wrong feeling. In fact, female also can’t ejaculate and urinate at the same time, because women also have a valve to keep it from being able to ejaculate and urinate at the same time. You will feel incredible, but it is a fact. Moreover, this valve not only can prevent women peeing during sex, but also can prevent women peeing right after the orgasm immediately, and women would obviously feel they need to wait for a few seconds to open somewhere hard to release the urine. A lot of people claim that urinary incontinence is female ejaculation. I think this theory is absurd and stupid. This is all because people can’t figure out what a real female orgasm yet.

2012年5月4日星期五

My inspiration from Pap test




The Pap test, also called a Pap smear, checks for changes in the cells of your cervix . The cervix is the lower part of the uterus (womb) that opens into the vagina (birth canal). The Pap test can tell if you have an infection, abnormal (unhealthy) cervical cells, or cervical cancer.









































The following two pictures are normal cells examined under a microscope in Pap test. I got very surprised, when I first saw these pictures from internet, because I found these pictures from cervix are very similar to my pictures.



After every time I orgasm, I can always feel there will be a little mucus to flow out from my vagina. I collected it from vagina opening and put it under a microscope. The following pictures are my mucus after my ejaculation under microscope.






The following pictures are stained by Trypan Blue




1, Obviously, I can see that the number of cells from vagina opening after my ejaculation is far more than they get from cervix in Pap test.

2, My cells can be stained by Trypan Blue, it means these cells are dead (PS: I orgasm and get the sample in evening first day, and I put the sample under microscope in morning second day, about 12 hours time lag.)



My curiosity:

1, Why I can ejaculate so many dead cells?
Because of the Pap test sampled from cervix at the bottom of the uterus, I have enough reason to deduce that my dead cells are from uterus inside through Os. It also means uterus will discharge some mucus including lots of dead cells from cervix, while female orgasm.


2, Where are these cells from?
As you known, menstrual discharge is composed from the inside of the uterus, but apparently far different from the ejaculation mucus. Female menstruation period is approximately every 28 days, but every orgasm in every time I can ejaculate some mucus like this. If I orgasm several times a night, I can definitely feel that the quantity of mucus are progressively reduced, if in seventh time, I nearly ejaculate nothing out. I do think ejaculation is a very complicated process as same as menstruation.

3, Does the mucus contain gametes? Unfertilized egg or polarbodys.
In male ejaculation, male discharge sperm form testis out of body, why can’t female discharge something from ovarian out of body in real female orgasm. Everything is possible. Current theory claims that the unfertilized egg either dissolves or is absorbed into the body, but I don’t know it. I don’t think uterus have absorption function, if that way, uterus can absorb all menstrual blood, not to discharge them. I guess uterus only have excretory function through Os, including menstrual blood, baby and ejaculation mucus.

There are too many mysteries waiting for me to unlock, I really need God’s help, I believe God is an American.